Linked Life Data

6391974

Source:http://linkedlifedata.com/resource/pubmed/id/6391974

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1985-2-21
pubmed:abstractText
Glucose at 1.7 and 5.6 mmol/l, pyruvate (30 mmol/l) and glutamine (10 mmol/l) all stimulated islet respiration slightly. More marked stimulation was achieved with glucose 8.3 mmol/l. When pyruvate (30 mmol/l) was added to islets respiring in the presence of different concentrations of glucose (1.7, 3.3 or 5.6 mmol/l), a stimulatory effect was only observed at the highest glucose concentration. Stimulation of islet oxygen uptake was also achieved when glucose 8.3 (but not 5.6) mmol/l was added to islets respiring in glutamine 10 mmol/l. Radioactive nucleotide efflux was, however, progressively inhibited by increasing the glucose concentration up to 5.6 mmol/l both in the absence or presence of glutamine 10 mmol/l. It is concluded that the glucose-induced inhibition of radioactive nucleotide efflux is not obligatorily linked to respiration.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0338-1684
pubmed:author
pubmed:issnType
Print
pubmed:volume
10
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
230-4
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Glucose induced inhibition of radioactive nucleotide efflux from mouse pancreatic islets is dissociated from an increase in islet oxygen uptake.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't