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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
10
|
pubmed:dateCreated |
1985-1-9
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pubmed:abstractText |
Captopril disulfides and the drug covalently bound to proteins were reduced with tri-n-butylphosphine. After sample purification on an XAD-2 column, captopril was treated with 1-(7-dimethylamino)-4-methyl-2-oxo-2H -1-benzopyran-3-yl)-1H-pyrrole-2,5-dione to form a fluorescent derivative. After acidification, the fluorescent derivative was extracted into toluene and purified on a C18 cartridge. The fluorescence of the dimethyl-formamide eluate was measured at an excitation wavelength of 380 nm and a fluorescence wavelength of 440 nm.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0022-3549
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
73
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1427-30
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading | |
pubmed:year |
1984
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pubmed:articleTitle |
Spectrofluorometric determination of captopril plus captopril disulfide metabolites in plasma.
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pubmed:publicationType |
Journal Article
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