Linked Life Data

6387783

Source:http://linkedlifedata.com/resource/pubmed/id/6387783

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1984-12-18
pubmed:abstractText
The effects on cardiac hemodynamics and serum parameters of a standard contrast agent (sodium methylglucamine diatrizoate [Renografin 76]) were compared with the effects of a new nonionic agent (iohexol) in a double-blind study in 51 patients undergoing coronary angiography and left ventriculography. No significant alteration in measured blood parameters occurred with either contrast agent. Hemodynamic changes occurred with both, but were significantly greater with the standard Renografin than with the low-osmolality, nonionic iohexol. After left ventriculography, heart rate increased and peripheral arterial pressure fell with both agents, but less with iohexol. Following coronary artery injections, heart rate and arterial pressure decreased with both agents, but the changes were more marked and occurred earlier with the standard contrast material. It is concluded that iohexol causes less alteration in cardiac function than does the agent currently most widely used. Nonionic contrast material is likely to improve the safety of coronary angiography, particularly in those patients at greatest risk.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0033-8419
pubmed:author
pubmed:issnType
Print
pubmed:volume
153
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
583-7
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Contrast agents for cardiac angiography: effects of a nonionic agent vs. a standard ionic agent.
pubmed:publicationType
Journal Article, Clinical Trial, Comparative Study, Research Support, Non-U.S. Gov't