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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1984-11-28
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pubmed:abstractText |
The dual properties of two human retinoblastoma cell lines, WERI-Rb1 and Y79, were investigated with immunohistochemistry. Two neuron-specific markers, dopamine-B-hydroxylase (DBH) and tetanus toxin, and an astrocyte-specific marker, the glial fibrillary acid protein (GFAP), were applied for immunohistochemical reactions. With peroxidase-antiperoxidase (PAP) and immunofluorescence techniques, all of the WERI-Rb1 and Y79 cells showed consistently positive results with both neuronal and glial markers. The findings demonstrate that cultured retinoblastoma cells WERI-Rb1 and Y79 have both neuronal and glial properties.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0014-4835
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
39
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
207-15
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:6386499-Cell Line,
pubmed-meshheading:6386499-Cells, Cultured,
pubmed-meshheading:6386499-Dopamine beta-Hydroxylase,
pubmed-meshheading:6386499-Eye Neoplasms,
pubmed-meshheading:6386499-Fluorescent Antibody Technique,
pubmed-meshheading:6386499-Glial Fibrillary Acidic Protein,
pubmed-meshheading:6386499-Humans,
pubmed-meshheading:6386499-Immunoenzyme Techniques,
pubmed-meshheading:6386499-Neuroglia,
pubmed-meshheading:6386499-Neurons,
pubmed-meshheading:6386499-Retinoblastoma,
pubmed-meshheading:6386499-Tetanus Toxin
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pubmed:year |
1984
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pubmed:articleTitle |
Dual properties of cultured retinoblastoma cells: immunohistochemical characterization of neuronal and glial markers.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.
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