Linked Life Data

6384504

Source:http://linkedlifedata.com/resource/pubmed/id/6384504

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1984-11-21
pubmed:abstractText
In rats immunized with native type II collagen the number of lymphocytes secreting anti-type II collagen antibodies was enumerated in the lymph nodes using the direct hemolytic plaque assay. Arthritic rats had more lymphocytes, more plaque forming cells to native type II collagen and higher levels of serum IgM antibody to native type II collagen than nonarthritic rats. In vitro incubation of lymphocytes with native type II collagen before the plaque assay greatly increased the number of plaque forming cells from arthritic rats but not from nonarthritic rats. These findings suggest that arthritic rats had greater reactivity to native type II collagen and were less able to control the humoral response to collagen than were nonarthritic rats.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0315-162X
pubmed:author
pubmed:issnType
Print
pubmed:volume
11
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
432-7
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Native type II collagen-induced arthritis in the rat. Studies of the humoral response to collagen at the cellular level.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't