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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1984-11-21
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pubmed:abstractText |
To assess the importance of glucose uptake by muscle in determining total glucose utilization in the basal state, forearm glucose uptake (FGU), reflecting mainly skeletal muscle metabolism, and glucose turnover using [3-3H]glucose were studied simultaneously in 17 postabsorptive normal men. Mean +/- SE glucose disappearance was 2.36 +/- 0.14 mg/kg X min, amounting to 170 +/- 9 mg/min, while FGU was 0.049 +/- 0.009 mg/100 ml forearm X min. When the latter was calculated in terms of skeletal muscle in the body as a whole, muscle glucose utilization was found to be 24.7 +/- 4.5 mg/min, comprising only 13.5 +/- 1.9% of the total glucose disappearance. Forearm oxygen consumption was 6.6 +/- 0.5 mumol/100 ml forearm X min, of which only 26 +/- 5% could be accounted for by concurrent glucose uptake. These results suggest that in the basal state, glucose uptake by skeletal muscle accounts for 1) only a small percentage of total glucose disappearance and 2) only a minor proportion of peripheral oxygen consumption, which may be more dependent on lipid oxidation.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0021-972X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
59
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
857-60
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:6384259-Adult,
pubmed-meshheading:6384259-Blood Glucose,
pubmed-meshheading:6384259-Forearm,
pubmed-meshheading:6384259-Glucose,
pubmed-meshheading:6384259-Humans,
pubmed-meshheading:6384259-Lactates,
pubmed-meshheading:6384259-Lactic Acid,
pubmed-meshheading:6384259-Male,
pubmed-meshheading:6384259-Metabolic Clearance Rate,
pubmed-meshheading:6384259-Muscles,
pubmed-meshheading:6384259-Oxidation-Reduction,
pubmed-meshheading:6384259-Oxygen Consumption,
pubmed-meshheading:6384259-Radioisotope Dilution Technique
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pubmed:year |
1984
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pubmed:articleTitle |
Relationship among peripheral glucose uptake, oxygen consumption, and glucose turnover in postabsorptive man.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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