Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-5
pubmed:dateCreated
1984-6-13
pubmed:abstractText
Significative modifications in cartilage matrix are induced by GuHCl 4 M and 0.4 M treatment. The first treatment (4 M) induces a complete lack of interfibrillar alcianophilic particles and the swelling of collagen fibrils in 8 nm (80 A) thin aperiodic microfilaments. Among microfilaments, come alcianophilic sheets are often present ( unextractable proteoglycans?). The rectilinear pattern of filaments inside the fibrils became helicoidal. The second treatment (0.4 M) does not modify the interfibrillar morphology of alcianophilic rod like particles but may swell collagen fibril. Aldehydic fixation completely prevents such modifications. These observations show that organization of periodic collagen fibrils is probably due to proteoglycans also.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0003-2786
pubmed:author
pubmed:issnType
Print
pubmed:volume
155
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
57-64
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Ultrastructural modifications of cartilage matrix treated with guanidinium HCl (4.0 M and 0.4 M).
pubmed:publicationType
Journal Article