Switch to
Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1984-6-8
|
pubmed:abstractText |
A 35-year-old man, who had been ingesting one or two bags of tablets of pure licorice daily (20-40 g/day) for about two years, developed an acute myopathy with high levels of serum muscle enzymes and the typical features of mineralocorticoid excess: serious hypokalemia, hypertension, metabolic alkalosis. Both plasma renin and serum aldosterone were below the normal values. Ultrastructural study of muscle showed only minor, aspecific changes. Glycyrrhizinic acid, a steroid-like glycoside contained in natural licorice, has a well-known mineralocorticoid activity but severe potassium depletion and rhabdomyolysis due to chronic licorice ingestion have rarely been reported. This case further indicates that such a possibility is to be considered in the differential diagnosis of a patient admitted because of acute flaccid tetraparesis and hypokalemia.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Dec
|
pubmed:issn |
0392-0461
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
4
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
493-7
|
pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:6370909-Adult,
pubmed-meshheading:6370909-Aldosterone,
pubmed-meshheading:6370909-Glycyrrhiza,
pubmed-meshheading:6370909-Humans,
pubmed-meshheading:6370909-Hypokalemia,
pubmed-meshheading:6370909-Male,
pubmed-meshheading:6370909-Microscopy, Electron,
pubmed-meshheading:6370909-Mitochondria, Muscle,
pubmed-meshheading:6370909-Muscles,
pubmed-meshheading:6370909-Plants, Medicinal,
pubmed-meshheading:6370909-Renin,
pubmed-meshheading:6370909-Rhabdomyolysis
|
pubmed:year |
1983
|
pubmed:articleTitle |
Acute hypokalemic myopathy due to chronic licorice ingestion: report of a case.
|
pubmed:publicationType |
Journal Article,
Case Reports
|