Linked Life Data

6370528

Source:http://linkedlifedata.com/resource/pubmed/id/6370528

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1984-6-14
pubmed:abstractText
A 75-year-old female with a remote history of electroconvulsive-shock therapy and more recent care for psychotic depression died due to thromboembolic disease. Intranuclear inclusions were found to be widespread in her brain after autopsy. There was a paucity of the usual pathologic findings of herpes simplex virus (HSV) encephalitis, but light microscopic studies using antiserum to HSV type 1 demonstrated the presence of this agent in the intranuclear inclusions and in the cytoplasm of neurons and glial cells using immunoperoxidase staining methods. Immunostaining was also performed at the ultrastructural level and virus-like particles were identified. No immunostaining was obtained using normal control serum or antiserum to HSV type 2, while HSV type 1 or type 2 was demonstrated by immunostaining in control tissues. Control brain tissue from a group of psychotic and non-psychotic patients failed to show immunostaining for HSV antigen. This case is discussed in light of the current evidence pointing to a link between viral disease and psychosis.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0722-5091
pubmed:author
pubmed:issnType
Print
pubmed:volume
3
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
59-67
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:articleTitle
Immunoperoxidase demonstration of herpes simplex virus type 1 in the brain of a psychotic patient without history of encephalitis.
pubmed:publicationType
Journal Article, Case Reports