Linked Life Data

6368518

Source:http://linkedlifedata.com/resource/pubmed/id/6368518

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1984-5-2
pubmed:abstractText
Sixteen episodes of peritonitis in 13 patients undergoing continuous ambulatory peritoneal dialysis (CAPD) were treated with oral cephalexin given at each 6-hourly dialysate exchange. Serial measurements of the antibiotic concentration in serum and dialysate were made in seven cases. Cephalexin levels increased rapidly and by 12 h exceeded 27 mg/l in serum and 20 mg/l in dialysate. Dialysate levels considerably exceeded the minimum bactericidal concentration for organisms considered cephalexin-sensitive and in patients with these the clinical response was usually good. Although dialysate concentrations sometimes reached the minimum inhibitory concentration for organisms considered cephalexin-resistant the clinical response in patients from whom resistant bacteria were cultured was unsatisfactory. Intra-peritoneal antibiotic administration would seem unnecessary in many CAPD patients with peritonitis.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0305-7453
pubmed:author
pubmed:issnType
Print
pubmed:volume
13
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
153-9
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Cephalexin for the oral treatment of CAPD peritonitis.
pubmed:publicationType
Journal Article