Switch to
Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1984-5-17
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pubmed:abstractText |
15 insulin-dependent diabetic children at onset were randomly allocated to one of two different therapeutical protocols: continuous subcutaneous insulin infusion (CSII) and intensified conventional insulin treatment with three daily insulin injections (CIT). Both treatments were performed for 10 days; the initial insulin dose was 1.5 U/kg/day and thereafter the insulin dosage was modified in order to obtain a satisfactory control. Near-normal blood glucose levels were obtained after 24 h in the CSII group, and after 3 days in the CIT group. All subjects underwent 1 year of follow-up. HbA1 levels and insulin requirements decreased similarly in the two groups; C-peptide secretion did not increase significantly in both groups. A clear advantage of CSII cannot be assumed, and the usefulness of this therapeutical approach needs to be confirmed by further investigations.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0301-0163
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
19
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
65-9
|
pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:6368353-Adolescent,
pubmed-meshheading:6368353-C-Peptide,
pubmed-meshheading:6368353-Child,
pubmed-meshheading:6368353-Child, Preschool,
pubmed-meshheading:6368353-Diabetes Mellitus, Type 1,
pubmed-meshheading:6368353-Female,
pubmed-meshheading:6368353-Follow-Up Studies,
pubmed-meshheading:6368353-Hemoglobin A, Glycosylated,
pubmed-meshheading:6368353-Humans,
pubmed-meshheading:6368353-Insulin,
pubmed-meshheading:6368353-Insulin Infusion Systems,
pubmed-meshheading:6368353-Male,
pubmed-meshheading:6368353-Remission, Spontaneous
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pubmed:year |
1984
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pubmed:articleTitle |
Metabolic control in newly diagnosed type 1 diabetic children. Effect of continuous subcutaneous infusion.
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
|