Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1984-3-5
|
pubmed:abstractText |
We conducted a prospective, randomized, double-blind therapeutic trial of vitamin E as an erythropoietic agent in a group of patients with chronic renal failure who were undergoing chronic hemodialysis. Sixteen patients received 400 IU of vitamin E (d-alpha-tocopheryl acetate) by mouth twice daily and 19 patients received a placebo twice daily for 20 wk. The serum vitamin E concentration increased from 1.3 to 2.6 mg/dl in the treated group and decreased from 1.3 to 1.1 in the placebo group. For the treated group the initial hematocrit was 24.8 +/- 3.0 (mean +/- SD) and the final hematocrit was 25.8 +/- 3.8. For the placebo group the initial hematocrit was 24.9 +/- 3.0 and the final hematocrit was 23.5 +/- 2.7. The treated group received a total of 40 blood transfusions, and the placebo group received a total of 35 blood transfusions. Thus, vitamin E had no effect on the anemia or transfusion requirements of patients undergoing chronic hemodialysis for chronic renal failure.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
AIM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Feb
|
pubmed:issn |
0002-9165
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
39
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
223-6
|
pubmed:dateRevised |
2007-11-15
|
pubmed:meshHeading |
pubmed-meshheading:6364774-Anemia,
pubmed-meshheading:6364774-Blood Transfusion,
pubmed-meshheading:6364774-Clinical Trials as Topic,
pubmed-meshheading:6364774-Double-Blind Method,
pubmed-meshheading:6364774-Erythrocyte Aging,
pubmed-meshheading:6364774-Erythropoiesis,
pubmed-meshheading:6364774-Female,
pubmed-meshheading:6364774-Hematocrit,
pubmed-meshheading:6364774-Humans,
pubmed-meshheading:6364774-Kidney Failure, Chronic,
pubmed-meshheading:6364774-Male,
pubmed-meshheading:6364774-Middle Aged,
pubmed-meshheading:6364774-Prospective Studies,
pubmed-meshheading:6364774-Random Allocation,
pubmed-meshheading:6364774-Renal Dialysis,
pubmed-meshheading:6364774-Vitamin E
|
pubmed:year |
1984
|
pubmed:articleTitle |
Lack of effect of vitamin E therapy on the anemia of patients receiving hemodialysis.
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, U.S. Gov't, Non-P.H.S.,
Randomized Controlled Trial
|