Linked Life Data

6364338

Source:http://linkedlifedata.com/resource/pubmed/id/6364338

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
52
pubmed:dateCreated
1984-3-1
pubmed:abstractText
The usefulness of captopril in managing hypertensive emergencies was evaluated in 9 untreated patients. During the 30 minutes following oral administration of 25 mg of this angiotensin converting enzyme inhibitor, blood pressure decreased from 239/134 to 204/118 mm Hg (p less than 0.05). At that time, furosemide (20 mg i.v. or 40 mg orally) had to be added in 5 patients to further decrease pressure levels. Ninety to 120 minutes after starting therapy, an additional dose of captopril (100 mg orally) was given to all patients. 12 and 24 hours after admission respectively, blood pressure averaged 140/93 and 139/86 mm Hg in the patients treated with captopril alone and 166/107 and 153/91 mm Hg in those treated with both captopril and furosemide. The blood pressure fall was well tolerated and no adverse effect was induced by captopril. These results show that captopril given alone or in association with a diuretic makes it possible to deal quickly and effectively with hypertensive crises without necessarily requiring monitoring in an intensive care unit.
pubmed:language
fre
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0036-7672
pubmed:author
pubmed:issnType
Print
pubmed:day
31
pubmed:volume
113
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2006-7
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
[Treatment of hypertensive crisis with captopril].
pubmed:publicationType
Journal Article, English Abstract