Linked Life Data

6363708

Source:http://linkedlifedata.com/resource/pubmed/id/6363708

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1984-3-16
pubmed:abstractText
The virulence of 93 clinical isolates of Klebsiella was compared in a mouse model by subcutaneous injection. Skin pathogenicity was measured by estimating the number of viable bacteria in the lesions 24 h after infection with a dose of 10(7) bacteria. Strains of serotypes K1-6 were compared with strains of serotypes higher than K6. All K1 and K5, and some K2 and K4 strains were more virulent for mice than strains with a serotype higher than K6. The K3 strains were significantly less virulent than the strains with a serotype higher than K6. The bacteriological findings were confirmed by histological examination with some strains. No differences in virulence were observed between strains of the same serotype isolated from patients with cystitis or from those with pyelonephritis, nor between strains of the same serotype isolated from the blood of patients with septicaemia or from other sites. The mouse model has been found satisfactory for observing differences in virulence between Klebsiella isolates.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0022-2615
pubmed:author
pubmed:issnType
Print
pubmed:volume
17
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
67-77
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Virulence of Klebsiella strains in experimentally induced skin lesions in the mouse.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't