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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1984-3-6
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pubmed:abstractText |
The metabolic capacity of interscapular brown adipose tissue of hypoinsulinemic (diabetic) rats is decreased and a reduced beta-oxidative capacity contributes to this metabolic alteration. It was thus of interest to compare, in diabetic and in chronically (8 days) insulin-infused rats, the beta-oxidative capacity and indices of the thermogenic state (GDP-binding and 32 000 Mr protein) in this tissue. Mitochondrial GDP-binding and 32 000 Mr protein were both decreased in diabetic rats compared to appropriate controls and markedly increased as was also the beta-oxidative capacity in hyperinsulinemic rats.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0014-5793
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
23
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pubmed:volume |
166
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
141-5
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:6363125-Adipose Tissue,
pubmed-meshheading:6363125-Animals,
pubmed-meshheading:6363125-Body Temperature Regulation,
pubmed-meshheading:6363125-Diabetes Mellitus, Experimental,
pubmed-meshheading:6363125-Fatty Acids,
pubmed-meshheading:6363125-Guanosine Diphosphate,
pubmed-meshheading:6363125-Hydrogen-Ion Concentration,
pubmed-meshheading:6363125-Insulin,
pubmed-meshheading:6363125-Mitochondria,
pubmed-meshheading:6363125-NAD,
pubmed-meshheading:6363125-Oxidation-Reduction,
pubmed-meshheading:6363125-Proteins,
pubmed-meshheading:6363125-Rats
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pubmed:year |
1984
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pubmed:articleTitle |
Modulation of beta-oxidation and proton conductance pathway of brown adipose tissue in hypo- and hyperinsulinemic states.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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