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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1984-2-14
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pubmed:abstractText |
Shigella dysenteriae type 1 was used to study the influence of aeration on enterotoxin production and the suitability of laboratory animals for the toxin assay. The enterotoxin produced under aerobic shake culture conditions gave a gut dilatory response of 1.436 but that obtained in aerobic and anaerobic stationary cultures exerted no activity. The toxin fractionated on Sephadex G-150 column was more effective than that obtained by ammonium sulphate precipitation. Only Sephadex column fraction II had a toxic activity. Among the three laboratory animal models tested, the rabbit ileal loop was suitable for the assay of toxin. The skin permeability test was unsatisfactory for enterotoxicity assay.
|
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0231-4622
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
30
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
147-53
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:6362316-Aerobiosis,
pubmed-meshheading:6362316-Animals,
pubmed-meshheading:6362316-Biological Assay,
pubmed-meshheading:6362316-Enterotoxins,
pubmed-meshheading:6362316-Ileum,
pubmed-meshheading:6362316-Permeability,
pubmed-meshheading:6362316-Rabbits,
pubmed-meshheading:6362316-Rats,
pubmed-meshheading:6362316-Shigella dysenteriae,
pubmed-meshheading:6362316-Skin Physiological Phenomena
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pubmed:year |
1983
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pubmed:articleTitle |
Studies of enterotoxin of Shigella dysenteriae type 1. I. Effect of aeration on the production of enterotoxin and suitability of laboratory animals for its biological assay.
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pubmed:publicationType |
Journal Article,
Comparative Study
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