Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1984-2-14
pubmed:abstractText
Shigella dysenteriae type 1 was used to study the influence of aeration on enterotoxin production and the suitability of laboratory animals for the toxin assay. The enterotoxin produced under aerobic shake culture conditions gave a gut dilatory response of 1.436 but that obtained in aerobic and anaerobic stationary cultures exerted no activity. The toxin fractionated on Sephadex G-150 column was more effective than that obtained by ammonium sulphate precipitation. Only Sephadex column fraction II had a toxic activity. Among the three laboratory animal models tested, the rabbit ileal loop was suitable for the assay of toxin. The skin permeability test was unsatisfactory for enterotoxicity assay.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0231-4622
pubmed:author
pubmed:issnType
Print
pubmed:volume
30
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
147-53
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Studies of enterotoxin of Shigella dysenteriae type 1. I. Effect of aeration on the production of enterotoxin and suitability of laboratory animals for its biological assay.
pubmed:publicationType
Journal Article, Comparative Study