Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1984-1-27
pubmed:abstractText
The indirect assessment of prostacyclin synthetase by analysis of prostaglandin I2 (PGI2) formation in lung tissues of fetal, newborn and adult Swiss mice was determined by in vitro platelet inhibition. PGI2 was synthesized in fetal, newborn and adult mice lung tissues. A progressive increase in PGI2 synthesis with increasing fetal age was shown. The 11 to 13 days fetal age samples gave PGI2 values of 12.0 and 20 ng per 50 mg lung tissue, respectively. These represented 20% and 33% of the adult mean value of 60 ng. Adult levels of PGI2 were attained in utero at fetal age of 16 days. It is suggested that because of its early appearance in fetal life in the lung tissue, prostacyclin synthetase is an important enzyme in prostaglandin metabolism in the ontogeny of the fetus.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0034-5164
pubmed:author
pubmed:issnType
Print
pubmed:volume
42
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
145-8
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Prostaglandin I2 (prostacyclin) formation in lung tissues of Swiss mice.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't