Linked Life Data

6357428

Source:http://linkedlifedata.com/resource/pubmed/id/6357428

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
1984-1-7
pubmed:abstractText
In the decade since Breslow first described the technique of measuring tumor thickness in cutaneous melanoma and its prognostic significance, this measurement has become an integral part of the histologic evaluation of these tumors. In an attempt to define the effect of specimen sampling on this measurement, the authors compared their routine sampling method in which microscopic sections were examined at consecutive 3 mm intervals with one utilizing sequential microscopic serial sections of approximately 5 microns each in 19 cases of thin (less than 0.76 mm in depth) superficial spreading melanomas. All cases showed an increase in the measured maximum tumor thickness when serially sectioned, but neither deep dermal extension of melanoma nor angiolymphatic invasion by tumor were observed. Measured thickness in thin cutaneous melanoma is a function of the number of sections examined. The method of specimen sampling needs to be carefully defined and standardized in studies that attempt to define prognosis on the basis of tumor thickness. It is proposed that the routine sampling technique of the authors meets these criteria and that it be adopted as a standardized method of examining pigmented cutaneous specimens.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0008-543X
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
52
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2338-41
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
An evaluation of vertical growth in thin superficial spreading melanomas by sequential serial microscopic sections.
pubmed:publicationType
Journal Article