Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1983-12-17
pubmed:abstractText
Monoclonal antibodies to human immunoglobulin M (IgM) were used in a four-phase enzyme immunofluorescence "capture" assay for determination of IgM antibodies to measles and rubella viruses. Little or no background reactivity was seen in the test system, and interfering effects of rheumatoid factor were avoided by preabsorption of test sera with aggregated human IgG. Virus-specific IgM antibody was demonstrable in 23 of 24 patients with serological evidence of measles virus infections and in 36 of 36 patients with serological evidence of postnatal rubella infection. A few of the rubella patients did not show IgM antibody until 5 days after onset of illness. The enzyme immunofluorescence assay was able to demonstrate rubella IgM antibody in congenitally infected newborns, whereas indirect immunofluorescence results for virus-specific IgM were negative. Viral IgM antibody was not detected in persons with past infections with the test viruses, in young children without evidence of past infection, or in patients infected with heterotypic viruses, rickettsiae, chlamydiae, or mycoplasmas.
pubmed:grant
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/6355153-14183399, http://linkedlifedata.com/resource/pubmed/commentcorrection/6355153-387813, http://linkedlifedata.com/resource/pubmed/commentcorrection/6355153-4316388, http://linkedlifedata.com/resource/pubmed/commentcorrection/6355153-4984203, http://linkedlifedata.com/resource/pubmed/commentcorrection/6355153-622392, http://linkedlifedata.com/resource/pubmed/commentcorrection/6355153-6262369, http://linkedlifedata.com/resource/pubmed/commentcorrection/6355153-6268655, http://linkedlifedata.com/resource/pubmed/commentcorrection/6355153-6752160, http://linkedlifedata.com/resource/pubmed/commentcorrection/6355153-6752345, http://linkedlifedata.com/resource/pubmed/commentcorrection/6355153-6819305, http://linkedlifedata.com/resource/pubmed/commentcorrection/6355153-7035501, http://linkedlifedata.com/resource/pubmed/commentcorrection/6355153-7080832, http://linkedlifedata.com/resource/pubmed/commentcorrection/6355153-7257775, http://linkedlifedata.com/resource/pubmed/commentcorrection/6355153-7462599, http://linkedlifedata.com/resource/pubmed/commentcorrection/6355153-78928
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0095-1137
pubmed:author
pubmed:issnType
Print
pubmed:volume
18
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
652-7
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Use of monoclonal antibodies to human immunoglobulin M in "capture" assays for measles and rubella immunoglobulin M.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.