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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1983-11-23
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pubmed:abstractText |
Studies utilizing glucose-controlled insulin infusion systems were undertaken to more accurately define the glucose and insulin requirements during the first stage of labor induced by oxytocin in 12 insulin-dependent diabetic women in whom normoglycemia had been maintained before delivery. Insulin requirements decreased to zero during active stage 1 labor, while the glucose infusion rate necessary to maintain a blood glucose level of 70 to 90 mg/dl (or 3.9 to 5.0 mmol/liter) was constant at 2.55 mg/kg per minute. The findings were confirmed in 40 additional studies of oxytocin-induced labor. Studies of six women undergoing spontaneous labor and one nonpregnant woman receiving oxytocin confirmed that the decrement in the insulin requirement during stage 1 labor was not influenced by oxytocin infusion. The changes occurred regardless of whether epidural anesthesia was employed. Insulin requirements returned during the second stage of labor. Active stage 1 labor in diabetic women thus appears to be associated with a predictable decrease in the need for insulin and a constant glucose requirement.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0002-9343
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
75
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
607-12
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:6353916-Blood Glucose,
pubmed-meshheading:6353916-Diabetes Mellitus, Type 1,
pubmed-meshheading:6353916-Female,
pubmed-meshheading:6353916-Glucose,
pubmed-meshheading:6353916-Humans,
pubmed-meshheading:6353916-Insulin,
pubmed-meshheading:6353916-Insulin Infusion Systems,
pubmed-meshheading:6353916-Labor, Induced,
pubmed-meshheading:6353916-Labor, Obstetric,
pubmed-meshheading:6353916-Labor Stage, First,
pubmed-meshheading:6353916-Pregnancy,
pubmed-meshheading:6353916-Pregnancy in Diabetics
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pubmed:year |
1983
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pubmed:articleTitle |
Insulin and glucose requirements during the first stage of labor in insulin-dependent diabetic women.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|