Linked Life Data

6352408

Source:http://linkedlifedata.com/resource/pubmed/id/6352408

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
1983-11-23
pubmed:abstractText
A number of rifampicin resistance mutations which have been mapped in the region of the rpoB gene, cause an increase in the activity level of a catabolite sensitive uridine phosphorylase (udp) gene. This effect is observed in bacterial cells deficient for the active protein repressor cytR, controlling expression of the udp gene. In cytR mutant cells grown on the medium containing glucose, the level of uridine phosphorylase is further increased by a factor of 1,5 to 2 under the influence of rif-r mutations. Concomitantly, the activity of some other catabolite sensitive genes controlled by the cytR protein is also increased on the medium with glucose. The data obtained suggest that the RNA polymerase beta-subunit participates in regulation of some catabolite sensitive genes.
pubmed:language
rus
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0016-6758
pubmed:author
pubmed:issnType
Print
pubmed:volume
19
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1070-4
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
[Mutations of resistance to rifampicin leading to increased activity of the uridine phosphorylase gene in Escherichia coli].
pubmed:publicationType
Journal Article, English Abstract