Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
10
|
pubmed:dateCreated |
1983-10-21
|
pubmed:abstractText |
To characterize the children with enuresis likely to respond to desmopressin acetate, we performed a double-blind crossover study that included the use of a placebo. During the two weeks of desmopressin administration, six children (12%) had 13 or 14 dry nights, and 15 children (29%) had eight to 12 dry nights. Among the 17 children aged 9 years or older, with four to seven dry nights during the two-week baseline period, 12 children (71%) responded to desmopressin (eight to 14 dry nights). In contrast, none of the 15 children younger than 9 years of age with fewer than three dry nights before therapy responded. During the posttreatment period, only four of the 21 drug responders reported a persistent effect. Desmopressin may be effective in reducing the frequency of enuresis, especially in children older than 9 years of age without nightly enuresis.
|
pubmed:grant | |
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
AIM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Oct
|
pubmed:issn |
0002-922X
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
137
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
962-3
|
pubmed:dateRevised |
2007-11-15
|
pubmed:meshHeading |
pubmed-meshheading:6351590-Adolescent,
pubmed-meshheading:6351590-Age Factors,
pubmed-meshheading:6351590-Arginine Vasopressin,
pubmed-meshheading:6351590-Child,
pubmed-meshheading:6351590-Clinical Trials as Topic,
pubmed-meshheading:6351590-Deamino Arginine Vasopressin,
pubmed-meshheading:6351590-Dose-Response Relationship, Drug,
pubmed-meshheading:6351590-Double-Blind Method,
pubmed-meshheading:6351590-Enuresis,
pubmed-meshheading:6351590-Female,
pubmed-meshheading:6351590-Humans,
pubmed-meshheading:6351590-Male,
pubmed-meshheading:6351590-Random Allocation
|
pubmed:year |
1983
|
pubmed:articleTitle |
Desmopressin response of enuretic children. Effects of age and frequency of enuresis.
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.,
Controlled Clinical Trial
|