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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1983-10-8
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pubmed:abstractText |
Three different histological techniques (scanning electron microscopy, phase contrast microscopy and light microscopy) were used to examine the organ of Corti after a damaging noise exposure. In the region of maximal injury, all outer hair cells were missing 1-2 h after the exposure had ended. Degenerated hair cells are eventually replaced by phalangeal scars. However, in these short-term recovery ears, a series of holes which were the exact size and shape of the missing outer hair cell apices were found in the reticular lamina. These holes may provide a communication route between the endolymphatic space and the fluid spaces of the organ of Corti for a period of time following a damaging noise exposure. The noise-related degeneration of supporting cells, nerve fibers and even some sensory cells may be secondary to contamination of the fluid spaces with potassium-rich endolymph.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0378-5955
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
11
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
41-53
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:6350251-Animals,
pubmed-meshheading:6350251-Cell Membrane,
pubmed-meshheading:6350251-Chinchilla,
pubmed-meshheading:6350251-Endolymph,
pubmed-meshheading:6350251-Hair Cells, Auditory,
pubmed-meshheading:6350251-Hearing Loss, Noise-Induced,
pubmed-meshheading:6350251-Microscopy, Electron, Scanning,
pubmed-meshheading:6350251-Microscopy, Phase-Contrast,
pubmed-meshheading:6350251-Nerve Fibers,
pubmed-meshheading:6350251-Organ of Corti,
pubmed-meshheading:6350251-Scala Tympani
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pubmed:year |
1983
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pubmed:articleTitle |
Holes in the reticular lamina after noise exposure: implication for continuing damage in the organ of Corti.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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