Linked Life Data

6348358

Source:http://linkedlifedata.com/resource/pubmed/id/6348358

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1983-9-20
pubmed:abstractText
Correlation between hemodynamic changes and plasma catecholamines or renin activity were studied in dogs anesthetized with pentobarbital, 30 mg/kg, i.v. Pentobarbital increased heart rate in all cases regardless of changes in plasma catecholamines, and the increase was not depressed fully by propranolol. Blood pressure (BP) showed a transient decline just after pentobarbital injection and then elevated gradually to one of three levels 30-60 min after anesthesia. In low (62 +/- 4 mmHg, Mean +/- S.E.) and very high BP (169 +/- 7 mmHg), plasma norepinephrine (NE) showed low (305 +/- 55 leads to 89 +/- 22 pg/ml) and high levels (296 +/- 54 leads to 372 +/- 106 pg/ml), respectively, which probably reflect the neurosympathetic activities. In moderately high BP (112 +/- 4 mmHg), however, the hypertension did not necessarily reflect changes in plasma NE. When the level before anesthesia was 108-164 pg/ml, plasma NE increased, whereas it decreased when the level was 182-374 pg/ml. In either case, the level was fixed within 117-182 (154 +/- 6) pg/ml. Plasma renin activity increased after anesthesia and maintained for at least 2 hr. However, the increase were observed regardless of the BP level, and moderately high BP was not depressed by an angiotensin II antagonist. Participation of angiotensin in these sustained BP cases seems unlikely. Plasma epinephrine reflecting adrenal-medullary activity was decreased markedly in all cases, and the low level lasted for at least 2 hr. Changes in plasma dopamine are related to those in plasma NE, and the origin seems to be the same.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0021-5198
pubmed:author
pubmed:issnType
Print
pubmed:volume
33
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
209-17
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Effects of pentobarbital anesthesia on the plasma catecholamines and renin activity as reflected in the hemodynamic changes in dogs.
pubmed:publicationType
Journal Article