Linked Life Data

6347

Source:http://linkedlifedata.com/resource/pubmed/id/6347

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1976-8-23
pubmed:abstractText
Changes in the properties of non-H-2 imcompatible skin allografts, resulting from treating the graft donors with whole-body irradiation, antilymphocyte serum, cyclophosphamide, hydrocortisone, amethopterin and azathioprine, affected differently their survival in the recipients pretreated with normal and antilymphocyte serum. While in NS--pretreated recipients the modified grafts showed the tendency for a prolonged survival, in ALS-pretreated recipients they survived for a shorter time than normal allografts. In ALS-pretreated recipients, also allografts from radiation chimaeras, whose blood-forming system was of the recipient's genotype, survived worse than normal allografts and grafts from the donor syngeneic radiation chimaeras. The findings indicate that a normal physiological state of the graft is necessary for the induction and working of the protective components of the allotrasplantation reaction involved in the graft survival promoting effect of ALS. The significance of passenger leucocytes and of the functional properties of the graft, especially of the reparation cellular and extracellular processes is discussed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0015-5500
pubmed:author
pubmed:issnType
Print
pubmed:volume
22
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
74-81
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1976
pubmed:articleTitle
Influence of the properties of skin allografts on the "graft survival promoting effect" of antilymphocyte serum.
pubmed:publicationType
Journal Article