Linked Life Data

6345945

Source:http://linkedlifedata.com/resource/pubmed/id/6345945

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1983-8-26
pubmed:abstractText
The ratio of the lactate dehydrogenase subunits, H/M, is shifted toward lower values in thymocytes, and in high-density T cells in normal peripheral blood. The results presented here indicate that the T cells, but not B cells or monocytes, of donors greater than 75 years' old have a significantly reduced H/M ratio relative to young adults. This reduced H/M ratio appears to be correlated with a diminished percentage of OKT3 positive cells in the old donors. However, the density distribution of cells from young and old on Percoll gradients indicates that the T cells with lower H/M ratio in the elderly may represent a distinct, and possibly unique, less differentiated T cell type.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0047-6374
pubmed:author
pubmed:issnType
Print
pubmed:volume
21
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
109-20
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Evidence for a less differentiated subpopulation of lymphocytes in people of advanced age.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't