rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
1983-5-5
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pubmed:abstractText |
Two multicentre, open comparative trials were carried out by seven dermatologists in Spain and Yugoslavia in 220 evaluable patients with acute superficial skin infections. In these trials halometasone/triclosan cream showed an overall success rate ('good' and 'very good' results) of 84% as against 60% obtained with the comparative preparations. With regard to therapeutic effect halometasone/triclosan cream proved significantly superior to fluocinolone acetonide/neomycin cream (p less than 0.001) and yielded a higher overall success rate, although not statistically significant, than that observed with fluprednylidene acetate/gentamicin/chlorohydroxyquinoline cream (75% versus 57%). The halometasone/triclosan cream was well tolerated: the incidence of unwanted effects was significantly lower (p less than 0.05) than that with fluocinolone acetonide/neomycin cream and equal to that with fluprednylidene acetate/gentamicin/chlorohydroxyquinoline cream.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0300-0605
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
11 Suppl 1
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
53-7
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:6339294-Administration, Topical,
pubmed-meshheading:6339294-Adolescent,
pubmed-meshheading:6339294-Adult,
pubmed-meshheading:6339294-Anti-Inflammatory Agents,
pubmed-meshheading:6339294-Bacterial Infections,
pubmed-meshheading:6339294-Betamethasone,
pubmed-meshheading:6339294-Clinical Trials as Topic,
pubmed-meshheading:6339294-Drug Combinations,
pubmed-meshheading:6339294-Female,
pubmed-meshheading:6339294-Fluocinolone Acetonide,
pubmed-meshheading:6339294-Humans,
pubmed-meshheading:6339294-Male,
pubmed-meshheading:6339294-Middle Aged,
pubmed-meshheading:6339294-Neomycin,
pubmed-meshheading:6339294-Phenyl Ethers,
pubmed-meshheading:6339294-Skin Diseases, Infectious,
pubmed-meshheading:6339294-Triclosan
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pubmed:year |
1983
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pubmed:articleTitle |
An overview of two comparative multicentre trials with halometasone/triclosan cream in acute superficial bacterial skin infections.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial
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