Linked Life Data

6338457

Source:http://linkedlifedata.com/resource/pubmed/id/6338457

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1983-4-15
pubmed:abstractText
Infection of cotton rats with Echinococcus multilocularis or vaccination with BCG, or its cell walls, activates peritoneal cells to kill the protoscolices of the parasite in vitro and protects laboratory animals against the cestode. To determine whether other 'non-specific' stimuli would also protect against the parasite, cotton rat peritoneal cells were activated in vivo with PHA and transferred to recipients 3 days later. The recipients, controls and PHA-treated animals were then inoculated with the parasite; 3 days after inoculation other untreated infected animals received cells activated in vivo with PHA. PHA-activated cells, the PHA treatment itself and immunization with a homogenate of the parasite stimulated a leucocytosis and protected against infection by E. multilocularis; carrageenan abrogated protection in PHA-treated animals. The results of this study confirm that protection against echinococcosis can be induced non-specifically; these results suggest that immunity in hydatid disease may have an important component in the inflammatory reaction.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0141-9838
pubmed:author
pubmed:issnType
Print
pubmed:volume
5
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
61-6
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Protection against experimental echinococcosis by non-specifically stimulated peritoneal cells.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't