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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
1983-4-21
|
| pubmed:abstractText |
An X-ray diffraction study of a zinc(II) complex of tRNAPhe from yeast reveals the present of five zinc-binding sites on the tRNA molecule. Two of the cooperatively bound Mg2+ in the native tRNA structure are replaced by Zn2+. The remaining sites involve direct coordination of zinc to the N7 position of tRNA guanine bases, G15, G43 and HG45. Thus, zinc displays a high specificity for binding to guanine bases in purine-purine sequences.
|
| pubmed:grant | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Mar
|
| pubmed:issn |
0006-3002
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
15
|
| pubmed:volume |
756
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
111-8
|
| pubmed:dateRevised |
2007-11-14
|
| pubmed:meshHeading |
pubmed-meshheading:6337651-Base Sequence,
pubmed-meshheading:6337651-Guanine,
pubmed-meshheading:6337651-Models, Molecular,
pubmed-meshheading:6337651-Nucleic Acid Conformation,
pubmed-meshheading:6337651-RNA, Transfer, Amino Acyl,
pubmed-meshheading:6337651-Saccharomyces cerevisiae,
pubmed-meshheading:6337651-X-Ray Diffraction,
pubmed-meshheading:6337651-Zinc
|
| pubmed:year |
1983
|
| pubmed:articleTitle |
X-ray diffraction study of the zinc(II) binding sites in yeast phenylalanine transfer RNA. Preferential binding of zinc to guanines in purine-purine sequences.
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|