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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1983-3-24
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pubmed:abstractText |
Primary mycobacterial infections developed in five of 565 patients who had transplants during a 15-year period. All had negative PPDs and normal chest roentgenograms; none had tuberculosis before transplantation. Atypical mycobacteria were cultured in three of five infections. All were treated with a multiple-drug regimen, including isoniazid, rifampin, ethambutol, and streptomycin sulfate. In four of five patients, there were serious drug-related complications. No major initial alteration of immunosuppressive therapy was necessary in any of the patients. During the study, a treatment policy was followed that included one year of isoniazid treatment of all recipients with a positive PPD, history of tuberculosis, chest x-ray film suggestive of tuberculosis, or PPD-positive donor. An additional 14 transplant recipients were treated in accordance with this policy without complications or subsequent mycobacterial infections (32-month average follow-up). Despite the low incidence of mycobacterial infection in this series, the potential lethality and morbidity mandate constant vigilance.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0004-0010
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
118
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
356-9
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:6337585-Adult,
pubmed-meshheading:6337585-Antitubercular Agents,
pubmed-meshheading:6337585-Female,
pubmed-meshheading:6337585-Humans,
pubmed-meshheading:6337585-Kidney Transplantation,
pubmed-meshheading:6337585-Male,
pubmed-meshheading:6337585-Mycobacterium Infections,
pubmed-meshheading:6337585-Mycobacterium Infections, Nontuberculous,
pubmed-meshheading:6337585-Premedication,
pubmed-meshheading:6337585-Preoperative Care
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pubmed:year |
1983
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pubmed:articleTitle |
Mycobacterial infections in renal allograft recipients.
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pubmed:publicationType |
Journal Article,
Case Reports
|