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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1983-3-24
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pubmed:databankReference | |
pubmed:abstractText |
The complete nucleotide sequence of the glucose-repressed alcohol dehydrogenase II gene (ADR2) from yeast has been established together with its 5'- and 3'-flanking regions. The limits of the gene have been determined by reverse transcriptase sequencing of the 5'-ends and by S1 nuclease mapping of the 3'-ends of the mature ADR2 mRNA. Comparison of the alcohol dehydrogenase I gene (ADC1) sequence (Bennetzen, J. L., and Hall, B.D. (1982) J. Biol. Chem. 257, 3018-3025) with that of ADR2 indicated four regions of sequence conservation in the 5'-flanking DNAs. One of these conserved regions contains the sequence TCAAG which may function as a yeast cap sequence. The coding sequence of ADR2 is 89% homologous with that of ADC1 and exhibits a bias in its codon utilization. Evidence is presented that the intergenic region at the 3'-end of the ADR2 gene is less than 550 base pairs.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Alcohol Dehydrogenase,
http://linkedlifedata.com/resource/pubmed/chemical/Alcohol Oxidoreductases,
http://linkedlifedata.com/resource/pubmed/chemical/Codon,
http://linkedlifedata.com/resource/pubmed/chemical/Glucose,
http://linkedlifedata.com/resource/pubmed/chemical/Isoenzymes
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0021-9258
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
25
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pubmed:volume |
258
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2674-82
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:6337160-Alcohol Dehydrogenase,
pubmed-meshheading:6337160-Alcohol Oxidoreductases,
pubmed-meshheading:6337160-Base Sequence,
pubmed-meshheading:6337160-Codon,
pubmed-meshheading:6337160-Gene Expression Regulation,
pubmed-meshheading:6337160-Genes,
pubmed-meshheading:6337160-Glucose,
pubmed-meshheading:6337160-Isoenzymes,
pubmed-meshheading:6337160-Saccharomyces cerevisiae
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pubmed:year |
1983
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pubmed:articleTitle |
Nucleotide sequence of the yeast alcohol dehydrogenase II gene.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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