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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1985-6-10
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pubmed:abstractText |
In vivo capillary examination was performed on 80 patients included in a prospective study of Raynaud phenomenon (RP): 40 RP only (RPO), 20 undifferentiated connective tissue disease (UCTD) and 20 systemic scleroderma (SD) of less than 5 years' duration. On initial examination, SD-pattern capillary abnormalities were found in 7/40 patients with RP alone, 18/20 with UCTD and 19/20 with SD. On follow-up a change of diagnosis into a definite connective tissue disease occurred in 4 patients with UCTD; one patient with RP alone died with symptoms of myositis and fulminant pulmonary vasculitis. All five showed SD-pattern capillary abnormalities of the "active" type on initial examination. A significant correlation between the "slow" capillary pattern and the presence of anticentromere antibodies was also observed. Only one patient of 25 RPO with normal capillaries available for follow-up showed any change in clinical status.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0392-856X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
1
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
195-205
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:6335855-Antibodies, Antinuclear,
pubmed-meshheading:6335855-Capillaries,
pubmed-meshheading:6335855-Connective Tissue Diseases,
pubmed-meshheading:6335855-Female,
pubmed-meshheading:6335855-Follow-Up Studies,
pubmed-meshheading:6335855-Humans,
pubmed-meshheading:6335855-Male,
pubmed-meshheading:6335855-Nails,
pubmed-meshheading:6335855-Prognosis,
pubmed-meshheading:6335855-Prospective Studies,
pubmed-meshheading:6335855-Raynaud Disease,
pubmed-meshheading:6335855-Scleroderma, Systemic,
pubmed-meshheading:6335855-Skin,
pubmed-meshheading:6335855-Telangiectasis,
pubmed-meshheading:6335855-Venules
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pubmed:articleTitle |
Microvascular abnormalities as possible predictors of disease subsets in Raynaud phenomenon and early connective tissue disease.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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