Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1985-6-13
pubmed:abstractText
The objective of this international collaborative study was to compare recent swine isolates of influenza viruses and determine whether significant antigenic differences among isolates from different areas of the world could be detected. H1N1 viruses isolated from pigs, birds and humans in 12 different countries were compared in haemagglutination-inhibition assays with post-infection ferret sera and monoclonal antibodies to H1N1 strains. Using A/NJ/8/76 as the reference strain, we found that recent swine isolates from Hong Kong, Italy, Japan, and the USA possess a haemagglutinin virtually indistinguishable from that of viruses typically associated with pigs, i.e., A/NJ/8/76. In contrast, recent swine isolates from several European countries (Belgium, Denmark, France, Federal Republic of Germany, and Spain) were distinguishable from A/NJ/8/76, as demonstrated by tests in the various laboratories. These studies suggest that the H1N1 viruses in pigs are antigenically heterogeneous and that the circulation of particular variants is associated with the geographical location of the animals. These results raise the question of whether these viruses originated from the same source, i.e., pigs, and have undergone antigenic drift or, alternatively, were introduced from other hosts, such as birds.
pubmed:grant
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/6335845-217205, http://linkedlifedata.com/resource/pubmed/commentcorrection/6335845-268647, http://linkedlifedata.com/resource/pubmed/commentcorrection/6335845-282644, http://linkedlifedata.com/resource/pubmed/commentcorrection/6335845-6164356, http://linkedlifedata.com/resource/pubmed/commentcorrection/6335845-6182687, http://linkedlifedata.com/resource/pubmed/commentcorrection/6335845-6243921, http://linkedlifedata.com/resource/pubmed/commentcorrection/6335845-6255900, http://linkedlifedata.com/resource/pubmed/commentcorrection/6335845-6292104, http://linkedlifedata.com/resource/pubmed/commentcorrection/6335845-6298942, http://linkedlifedata.com/resource/pubmed/commentcorrection/6335845-6623931, http://linkedlifedata.com/resource/pubmed/commentcorrection/6335845-6658105, http://linkedlifedata.com/resource/pubmed/commentcorrection/6335845-70881, http://linkedlifedata.com/resource/pubmed/commentcorrection/6335845-712123, http://linkedlifedata.com/resource/pubmed/commentcorrection/6335845-7309229, http://linkedlifedata.com/resource/pubmed/commentcorrection/6335845-74123, http://linkedlifedata.com/resource/pubmed/commentcorrection/6335845-81267, http://linkedlifedata.com/resource/pubmed/commentcorrection/6335845-825377, http://linkedlifedata.com/resource/pubmed/commentcorrection/6335845-88798
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0042-9686
pubmed:author
pubmed:issnType
Print
pubmed:volume
62
pubmed:owner
NLM
pubmed:authorsComplete
N
pubmed:pagination
871-8
pubmed:dateRevised
2010-10-26
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Antigenic comparisons of swine-influenza-like H1N1 isolates from pigs, birds and humans: an international collaborative study.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't