Linked Life Data

6335123

Source:http://linkedlifedata.com/resource/pubmed/id/6335123

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1985-3-6
pubmed:abstractText
We have developed a monocyte function test to determine the Interleukin 1 activity in lipopolysaccharide-stimulated monocyte culture supernatant, with or without the addition of indomethacin, in order to investigate helper and suppressor functions of monocytes in patients with chronic liver disease. Release of Interleukin 1 from monocytes was increased in patients with liver cirrhosis (p less than 0.01). Activity of suppressor monocytes was increased both in patients with chronic active hepatitis (p less than 0.01 and in those with liver cirrhosis (p less than 0.001). Since these disorders in the immunoregulatory function of monocytes were enhanced with advancement of liver dysfunction, we conclude that the liver plays an important role in maintaining normal monocyte function, and that chronic liver disease probably relates to dysfunction of monocytes.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0172-6390
pubmed:author
pubmed:issnType
Print
pubmed:volume
31
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
248-53
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Interleukin 1 activity in culture supernatant of lipopolysaccharide-stimulated monocytes from patients with chronic liver disease.
pubmed:publicationType
Journal Article