Linked Life Data

6334324

Source:http://linkedlifedata.com/resource/pubmed/id/6334324

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1985-1-3
pubmed:abstractText
The medial forebrain bundle (MFB) plays an important role in the central elaboration of male sexual behavior. However the role of its ascending monoaminergic systems is not well understood. By selective lesions of catecholaminergic and serotoninergic axons of the MFB, produced with 6-OHDA and 5-7-DHT respectively, its possible involvement in male sexual behavior was studied. The evaluation of the behavioral patterns was studied by means of a microcomputer which also permitted the quantification of sequences in the sexual behavior patterns. Lesions with 5-7 DHT increased the intromission-ejaculation sequences and the percentage of ejaculatory males, without modifying other behavioral tests. Lesions with 6-OHDA diminished the number of "active" sexual patterns and motor activity. In order to check the specificity of the chemical lesions, the in vitro uptake of labeled norepinephrine and serotonin was measured, 5-7 DHT lesioned rats show a reduction in the uptake of 5-HT-C14 in the MPOA while 6-OHDA group show a reduction of NA-H3 in the striatum.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0031-9384
pubmed:author
pubmed:issnType
Print
pubmed:volume
33
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
5-11
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Different roles of catecholaminergic and serotoninergic neurons of the medial forebrain bundle on male rat sexual behavior.
pubmed:publicationType
Journal Article