Linked Life Data

6334221

Source:http://linkedlifedata.com/resource/pubmed/id/6334221

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1984-12-27
pubmed:abstractText
In order to determine if increased injection pressures can alter the permeability and ultrastructure of blood vessels of the frog blood-nerve barrier, these vessels were examined following perfusion of the iliac artery at rates of 0.21 or 0.82 ml/min. At either perfusion rate, endoneurial blood vessel profiles were clearly evident and the surface area of these vessels amounted to 60% of the surface area of the perineurium. In all vessels a large number of vesicles were present within the endothelial cells. Many were attached by necks to one or the other plasma membrane, but no transcellular channels were evident. At the higher flow rate no changes in vesicles or junctions were seen, but blebs and blisters were evident at the luminal membranes of the endoneurial endothelium. When microperoxidase was perfused at 0.82 ml/min, reaction product frequently flooded the endothelial cells, was found as clumps on the cell surface, and was distributed within the endoneurial space. These changes represent the only ultrastructural evidence of endothelial cell damage and altered permeability in response to increased rate of perfusion.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0026-2862
pubmed:author
pubmed:issnType
Print
pubmed:volume
28
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
220-32
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Morphology of endoneurial blood vessels of frog sciatic nerve during vascular perfusion.
pubmed:publicationType
Journal Article