Linked Life Data

6334183

Source:http://linkedlifedata.com/resource/pubmed/id/6334183

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
1985-1-24
pubmed:abstractText
Sutherland and Weiss et al. reported cases of newborn human deaths or Gray syndrome after overdosage of chloramphenicol. In general, it has been reported that the acute toxicities of drugs are enhanced in immature animals compared with adult animals. The objective of this study was to determine the LD50 values in infant (5-day-old) and young adult (5-week-old) male and female mice after single subcutaneous and oral administration of MOM, non-crystalline solid and to estimate the toxicity ratio of those LD50 values. LD50 values of MOM, non-crystalline solid, were more than 5,000 mg/kg and the lethal toxicity was the same in infant and adult mice. Toxicity ratios were not obtained.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0368-2781
pubmed:author
pubmed:issnType
Print
pubmed:volume
37
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1565-8
pubmed:dateRevised
2009-11-11
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Toxicological studies on a new macrolide antibiotic, midecamycin acetate (miocamycin). Part VI-1. Acute toxicity in infant mice in comparison with young adult mice.
pubmed:publicationType
Journal Article, Comparative Study