Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
11
|
| pubmed:dateCreated |
1985-1-23
|
| pubmed:abstractText |
BALB/c nu/nu mice were grafted with embryonic 14-day-old C57BL/6 thymi which were transplanted either nontreated or after elimination of hemopoietic cells with 2-deoxyguanosine. In both types of grafts host cells developed normally into functional thymocytes. Thymocytes from 2-deoxyguanosine-treated but not from untreated grafts contained as many cytolytic T lymphocyte precursors specific for class I MHC antigens on thymus epithelium as normal BALB/c thymocytes. As cytolytic T lymphocyte precursors were neither suppressed nor activated in these grafts it is concluded that thymocytes ignore class I MHC antigens expressed on thymus epithelium.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Nov
|
| pubmed:issn |
0014-2980
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
14
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
1048-52
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:6333986-Animals,
pubmed-meshheading:6333986-Cells, Cultured,
pubmed-meshheading:6333986-Epithelium,
pubmed-meshheading:6333986-H-2 Antigens,
pubmed-meshheading:6333986-Major Histocompatibility Complex,
pubmed-meshheading:6333986-Mice,
pubmed-meshheading:6333986-Mice, Inbred Strains,
pubmed-meshheading:6333986-Mice, Nude,
pubmed-meshheading:6333986-Organ Culture Techniques,
pubmed-meshheading:6333986-T-Lymphocytes,
pubmed-meshheading:6333986-T-Lymphocytes, Cytotoxic,
pubmed-meshheading:6333986-Thymus Gland
|
| pubmed:year |
1984
|
| pubmed:articleTitle |
Thymocytes appear to ignore class I major histocompatibility complex antigens expressed on thymus epithelial cells.
|
| pubmed:publicationType |
Journal Article
|