Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1984-11-21
pubmed:abstractText
Sera of 153 children with rheumatic diseases were assayed by an enzyme-linked immunosorbent assay (ELISA) for the presence of antibodies to native (n) and to denatured (d) type II collagen (IIC). Among the study population, antibodies to nIIC were detected in 47% with juvenile rheumatoid arthritis (JRA), 21% with spondyloarthropathies, 37% with other rheumatic diseases, 70% with adult onset rheumatoid arthritis (RA), and in less than 1% of nonrheumatic disease control groups. Antibodies to dIIC were detected in 42% of children with JRA, 41% with spondyloarthropathies, 37% of children with other rheumatic diseases, 67% with adult onset RA, and in less than 6% of nonrheumatic disease control groups. These results indicate that, when compared to nonrheumatic disease control groups, antibodies to both nIIC and dIIC occur significantly more frequently in children with a variety of rheumatic diseases.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0315-162X
pubmed:author
pubmed:issnType
Print
pubmed:volume
11
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
425-31
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Antibodies to native and denatured type II collagen in children with rheumatic diseases.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't