pubmed:abstractText |
Newborn rat adrenocortical cells in primary culture have allowed us to establish the place of 11 beta/18-hydroxylation in the biosynthesis and metabolism of corticosteroid hormones. The affinity of the 11 beta/18-hydroxylation system has been determined with respect to known or potential intermediates. It has equally been examined in relation to 2 alpha-, 6 alpha-, 6 beta-, 16 alpha or 17 alpha-hydroxyprogesterone and 6 alpha-, 6 beta- or 17 alpha-hydroxy-11-deoxycorticosterone.
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