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rdf:type |
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lifeskim:mentions |
|
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pubmed:issue |
1
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pubmed:dateCreated |
1984-8-22
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pubmed:abstractText |
Mouse mammary tumor virus-specific DNA sequences endogenous to the BALB/c mouse are shown to exhibit variable levels of methylation in a tissue-specific manner. In DNA from both lactating mammary gland and spleen, MMTV-specific sequences were hypomethylated at specific HpaII and HhaI sites. These variably methylated sites were found in the terminal repetitive sequences of the endogenous viral genomes. The specific hypomethylation of a HpaII site in Mtv-9 is associated with expression of a 1.6 kb transcript in the lactating mammary gland.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0042-6822
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
136
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
69-77
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:6330997-5-Methylcytosine,
pubmed-meshheading:6330997-Animals,
pubmed-meshheading:6330997-Base Sequence,
pubmed-meshheading:6330997-Cytosine,
pubmed-meshheading:6330997-DNA, Viral,
pubmed-meshheading:6330997-DNA Restriction Enzymes,
pubmed-meshheading:6330997-Female,
pubmed-meshheading:6330997-Genes, Viral,
pubmed-meshheading:6330997-Lactation,
pubmed-meshheading:6330997-Mammary Glands, Animal,
pubmed-meshheading:6330997-Mammary Tumor Virus, Mouse,
pubmed-meshheading:6330997-Methylation,
pubmed-meshheading:6330997-Mice,
pubmed-meshheading:6330997-Mice, Inbred BALB C,
pubmed-meshheading:6330997-Pregnancy,
pubmed-meshheading:6330997-RNA, Viral,
pubmed-meshheading:6330997-Repetitive Sequences, Nucleic Acid,
pubmed-meshheading:6330997-Spleen,
pubmed-meshheading:6330997-Transcription, Genetic
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pubmed:year |
1984
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pubmed:articleTitle |
Mouse mammary tumor virus DNA methylation: tissue-specific variation.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|
