| pubmed-article:6330099 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:6330099 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:6330099 | lifeskim:mentions | umls-concept:C0021745 | lld:lifeskim |
| pubmed-article:6330099 | lifeskim:mentions | umls-concept:C0002199 | lld:lifeskim |
| pubmed-article:6330099 | lifeskim:mentions | umls-concept:C0597360 | lld:lifeskim |
| pubmed-article:6330099 | lifeskim:mentions | umls-concept:C1709059 | lld:lifeskim |
| pubmed-article:6330099 | pubmed:issue | 13 | lld:pubmed |
| pubmed-article:6330099 | pubmed:dateCreated | 1984-8-20 | lld:pubmed |
| pubmed-article:6330099 | pubmed:abstractText | The human neuroblastoma cell line T98G is sensitive to the antiproliferative activity of both alpha- and gamma-interferons (IFNs). Specific binding of a homogeneous 125I-IFN-alpha 2 probe to high-affinity membrane receptors (apparent Kd = 6.2 X 10(-10) M) can be decreased by pretreatment of these cells with human IFN-gamma (HuIFN-gamma, derived by recombinant DNA techniques). The regulation of HuIFN-alpha 2 binding by such pretreatment is reflected by subsequent inhibition of both the antiviral and antiproliferative activities of HuIFN-alpha 2 on T98G cells. Thus, binding of HuIFN-gamma to its distinct cell-surface receptor can modify expression of the separate IFN-alpha receptor, presumably through an indirect effect on the apparent Kd of the IFN-alpha 2 receptor-ligand interaction. | lld:pubmed |
| pubmed-article:6330099 | pubmed:language | eng | lld:pubmed |
| pubmed-article:6330099 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6330099 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:6330099 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6330099 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6330099 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6330099 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6330099 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:6330099 | pubmed:month | Jul | lld:pubmed |
| pubmed-article:6330099 | pubmed:issn | 0021-9258 | lld:pubmed |
| pubmed-article:6330099 | pubmed:author | pubmed-author:WilliamsB RBR | lld:pubmed |
| pubmed-article:6330099 | pubmed:author | pubmed-author:FishE NEN | lld:pubmed |
| pubmed-article:6330099 | pubmed:author | pubmed-author:HanniganG EGE | lld:pubmed |
| pubmed-article:6330099 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:6330099 | pubmed:day | 10 | lld:pubmed |
| pubmed-article:6330099 | pubmed:volume | 259 | lld:pubmed |
| pubmed-article:6330099 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:6330099 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:6330099 | pubmed:pagination | 8084-6 | lld:pubmed |
| pubmed-article:6330099 | pubmed:dateRevised | 2008-11-21 | lld:pubmed |
| pubmed-article:6330099 | pubmed:meshHeading | pubmed-meshheading:6330099-... | lld:pubmed |
| pubmed-article:6330099 | pubmed:meshHeading | pubmed-meshheading:6330099-... | lld:pubmed |
| pubmed-article:6330099 | pubmed:meshHeading | pubmed-meshheading:6330099-... | lld:pubmed |
| pubmed-article:6330099 | pubmed:meshHeading | pubmed-meshheading:6330099-... | lld:pubmed |
| pubmed-article:6330099 | pubmed:meshHeading | pubmed-meshheading:6330099-... | lld:pubmed |
| pubmed-article:6330099 | pubmed:meshHeading | pubmed-meshheading:6330099-... | lld:pubmed |
| pubmed-article:6330099 | pubmed:meshHeading | pubmed-meshheading:6330099-... | lld:pubmed |
| pubmed-article:6330099 | pubmed:meshHeading | pubmed-meshheading:6330099-... | lld:pubmed |
| pubmed-article:6330099 | pubmed:meshHeading | pubmed-meshheading:6330099-... | lld:pubmed |
| pubmed-article:6330099 | pubmed:year | 1984 | lld:pubmed |
| pubmed-article:6330099 | pubmed:articleTitle | Modulation of human interferon-alpha receptor expression by human interferon-gamma. | lld:pubmed |
| pubmed-article:6330099 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:6330099 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:6330099 | lld:pubmed |
