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Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1984-7-20
|
pubmed:abstractText |
The characteristics of the beta-adrenergic receptors in homogenates of fresh tissue and cultured bovine corneal epithelium were compared using [3H]dihydroalprenolol. High affinity, specific binding sites were observed in both preparations. Fresh tissue exhibited a higher binding site density (165 fmol/mg protein) than did cells in culture (57 fmol/mg protein). Studies with various beta-adrenergic agonists and antagonists indicated that binding characteristics were typical of beta-adrenergic receptors, predominantly of the beta 2 subtype. These results demonstrate that beta-adrenergic receptors exist in both fresh and cultured bovine corneal epithelium and that these receptors are qualitatively and quantitatively similar.
|
pubmed:grant | |
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jun
|
pubmed:issn |
0006-291X
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
15
|
pubmed:volume |
121
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
664-72
|
pubmed:dateRevised |
2007-11-14
|
pubmed:meshHeading |
pubmed-meshheading:6329207-Animals,
pubmed-meshheading:6329207-Binding, Competitive,
pubmed-meshheading:6329207-Cattle,
pubmed-meshheading:6329207-Cells, Cultured,
pubmed-meshheading:6329207-Cornea,
pubmed-meshheading:6329207-Cyclic AMP,
pubmed-meshheading:6329207-Dihydroalprenolol,
pubmed-meshheading:6329207-Epithelium,
pubmed-meshheading:6329207-Radioligand Assay,
pubmed-meshheading:6329207-Receptors, Adrenergic, beta
|
pubmed:year |
1984
|
pubmed:articleTitle |
Characteristics of beta-adrenergic receptors in bovine corneal epithelium: comparison of fresh tissue and cultured cells.
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|