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rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
3
|
|
pubmed:dateCreated |
1984-7-2
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|
pubmed:abstractText |
L-Carnitine protects mice against acute ammonia intoxication. The effect of L-carnitine on in vivo incorporation of [14C] bicarbonate into urea has been investigated in mice given large doses of ammonium acetate. The hepatic content of N-acetylglutamate has been measured. Following ammonia administration the animals given L-carnitine have much higher production of urea than the unprotected mice. The marked protective effect of L-carnitine on ammonium acetate-induced hyperammonemia and on the increase in urea synthesis is not due primarily to activation of N-acetylglutamate synthetase.
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|
pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
May
|
|
pubmed:issn |
0006-291X
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:day |
16
|
|
pubmed:volume |
120
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
726-33
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:6329182-Ammonia,
pubmed-meshheading:6329182-Animals,
pubmed-meshheading:6329182-Bicarbonates,
pubmed-meshheading:6329182-Carnitine,
pubmed-meshheading:6329182-Glutamates,
pubmed-meshheading:6329182-Male,
pubmed-meshheading:6329182-Mice,
pubmed-meshheading:6329182-Mitochondria, Liver,
pubmed-meshheading:6329182-Sodium Bicarbonate,
pubmed-meshheading:6329182-Urea
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|
pubmed:year |
1984
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|
pubmed:articleTitle |
Effects of L-carnitine on urea synthesis following acute ammonia intoxication in mice.
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|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
