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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3-4
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pubmed:dateCreated |
1984-6-11
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pubmed:abstractText |
Glycosylation of haemoglobin was evaluated in 30 normal adult Nigerians and 60 diabetic adult Nigerians who were at various stages of blood glucose control, by measuring ketoamine-linked hexoses in haemoglobin. These hexoses were converted by digestion with 1 M oxalic acid for 4.5 h at 100 degrees C to 5-hydroxymethylfurfural, which was measured by reaction with 2 thiobarbituric acid. Glycosylation of haemoglobin was expressed as micromoles (mumol) of fructose per 5% haemoglobin. A mean fructose concentration of 91.0 mumol/1 (s.d. +/- 9.3) was obtained for normal subjects; that for diabetic adult Nigerians was 175.3 mumol/l (s.d. +/- 26.4). There was significant correlation between fasting blood glucose levels and glycosylated haemoglobins in both normal adults (r = 0.77, P less than 0.001) and diabetic adults (r = 0.90, P less than 0.001). The colorimetric method was found to be precise and accurate with an interassay variability of 1.44% and an intra-assay variability of 0.98%.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0309-3913
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
177-82
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:6326552-Adult,
pubmed-meshheading:6326552-Blood Glucose,
pubmed-meshheading:6326552-Colorimetry,
pubmed-meshheading:6326552-Diabetes Mellitus, Type 2,
pubmed-meshheading:6326552-Female,
pubmed-meshheading:6326552-Hemoglobin A, Glycosylated,
pubmed-meshheading:6326552-Hemoglobinometry,
pubmed-meshheading:6326552-Humans,
pubmed-meshheading:6326552-Male
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pubmed:articleTitle |
HbA1C measured by a colorimetric method in normal and diabetic Nigerian subjects.
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pubmed:publicationType |
Journal Article
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