Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3-4
pubmed:dateCreated
1984-6-11
pubmed:abstractText
Glycosylation of haemoglobin was evaluated in 30 normal adult Nigerians and 60 diabetic adult Nigerians who were at various stages of blood glucose control, by measuring ketoamine-linked hexoses in haemoglobin. These hexoses were converted by digestion with 1 M oxalic acid for 4.5 h at 100 degrees C to 5-hydroxymethylfurfural, which was measured by reaction with 2 thiobarbituric acid. Glycosylation of haemoglobin was expressed as micromoles (mumol) of fructose per 5% haemoglobin. A mean fructose concentration of 91.0 mumol/1 (s.d. +/- 9.3) was obtained for normal subjects; that for diabetic adult Nigerians was 175.3 mumol/l (s.d. +/- 26.4). There was significant correlation between fasting blood glucose levels and glycosylated haemoglobins in both normal adults (r = 0.77, P less than 0.001) and diabetic adults (r = 0.90, P less than 0.001). The colorimetric method was found to be precise and accurate with an interassay variability of 1.44% and an intra-assay variability of 0.98%.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0309-3913
pubmed:author
pubmed:issnType
Print
pubmed:volume
12
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
177-82
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:articleTitle
HbA1C measured by a colorimetric method in normal and diabetic Nigerian subjects.
pubmed:publicationType
Journal Article