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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1984-6-19
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pubmed:abstractText |
GABA receptor activity, as measured by [3H]muscimol binding, was investigated in visual and auditory cortex of 5 weeks old kittens with different visual experience. Binocular deprivation since birth did not affect the GABA receptor binding activity. Three days of monocular vision resulted in an increase of [3H]muscimol binding in the visual cortex of both normally reared (144 percent) and binocularly deprived kittens (149 percent). Neither 3 days of normal binocular vision in deprived animals nor 3 days of binocular deprivation in normally reared ones produced significant changes in GABA receptor binding activity. In all experimental conditions [3H]muscimol binding in auditory cortex was similar. We suggest that activation of the GABA-ergic system is due to asymmetric visual input, possibly connected with mechanisms of ocular dominance shift.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0065-1400
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
44
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
33-9
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pubmed:dateRevised |
2011-1-7
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pubmed:meshHeading |
pubmed-meshheading:6326476-Animals,
pubmed-meshheading:6326476-Auditory Cortex,
pubmed-meshheading:6326476-Cats,
pubmed-meshheading:6326476-Muscimol,
pubmed-meshheading:6326476-Receptors, Cell Surface,
pubmed-meshheading:6326476-Receptors, GABA-A,
pubmed-meshheading:6326476-Visual Cortex,
pubmed-meshheading:6326476-Visual Perception
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pubmed:year |
1984
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pubmed:articleTitle |
Increase of GABA receptor binding activity after short lasting monocular deprivation in kittens.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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