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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1984-5-14
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pubmed:abstractText |
Screening of 70 asymptomatic homosexual men in Copenhagen revealed that 13 (19%) had T-helper to T-suppressor (H/S) ratios less than or equal to 1.0. Clinical and immunological follow-up examinations for 2-7 months (mean, 5.2 months) disclosed that none of the 13 men developed the acquired immunodeficiency syndrome (AIDS) or AIDS-like symptoms. An increase in H/S ratios to greater than 1.0 was observed in 11 of the 13 men during the time of observation. The decreased H/S ratios were due to an increase in the T-suppressor population. The T-helper population did not at any time differ from that found in 31 male control subjects. The biological relevance of the observed decrease in H/S ratios was supported by the demonstration of a positive correlation to a decrease in the proliferative response of the lymphocytes. Serological studies did not reveal any specific infectious background for the low H/S ratio found in the 13 men, and the reason for the 'spontaneous' increase during the time of observation remains unknown. The present results indicate that most asymptomatic homosexual men with a decreased H/S ratio will experience normalization of the immunological variables.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0300-9475
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
19
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
275-80
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pubmed:dateRevised |
2005-11-17
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pubmed:meshHeading |
pubmed-meshheading:6324334-Acquired Immunodeficiency Syndrome,
pubmed-meshheading:6324334-Antibodies, Viral,
pubmed-meshheading:6324334-Cytomegalovirus,
pubmed-meshheading:6324334-Homosexuality,
pubmed-meshheading:6324334-Humans,
pubmed-meshheading:6324334-Longitudinal Studies,
pubmed-meshheading:6324334-Male,
pubmed-meshheading:6324334-Prognosis,
pubmed-meshheading:6324334-T-Lymphocytes, Helper-Inducer,
pubmed-meshheading:6324334-T-Lymphocytes, Regulatory
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pubmed:year |
1984
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pubmed:articleTitle |
The prognosis of asymptomatic homosexual men with decreased T-helper to T-suppressor ratio.
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pubmed:publicationType |
Journal Article
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