|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0020852,
umls-concept:C0026473,
umls-concept:C0030685,
umls-concept:C0033554,
umls-concept:C0035448,
umls-concept:C0162745,
umls-concept:C0224522,
umls-concept:C0391871,
umls-concept:C0680255,
umls-concept:C0806987,
umls-concept:C1283071,
umls-concept:C1514503,
umls-concept:C1521761,
umls-concept:C1963578
|
|
pubmed:issue |
4
|
|
pubmed:dateCreated |
1984-4-4
|
|
pubmed:abstractText |
Self-associating IgG rheumatoid factors isolated from three patients with rheumatoid arthritis activated human monocytes to release prostaglandin E2 as well as a previously described mononuclear cell factor, which stimulates human synovial cells to release additional prostaglandin E2 and collagenase. Thus, the immune complexes composed of self-associating IgG rheumatoid factors can contribute to the processes that destroy cartilage and bone in patients with rheumatoid arthritis.
|
|
pubmed:grant |
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:issn |
0172-8172
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
3
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
183-6
|
|
pubmed:dateRevised |
2007-11-14
|
|
pubmed:meshHeading |
|
|
pubmed:year |
1983
|
|
pubmed:articleTitle |
Self-associating IgG rheumatoid factors stimulate monocytes to release prostaglandins and mononuclear cell factor that stimulates collagenase and prostaglandin production by synovial cells.
|
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|
