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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1984-4-13
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pubmed:abstractText |
We performed a clinical-pathologic review of 231 patients with early breast cancer treated by primary radiation therapy. There were 27 patients with infiltrating ductal carcinoma treated with excisional biopsy whose tumors showed a constellation of histologic features: moderate or marked intraductal carcinoma in the tumor, intraductal carcinoma in the adjacent tissue, and high nuclear grade. These patients had a 5-yr local tumor control rate of 61% compared to 96% for similar patients whose tumors did not show all three features. Radiation dose to the primary tumor area influenced the likelihood of local recurrence in these 27 patients: 15 of these patients received 6000 rads or more to the primary tumor area and had a 5-yr local tumor control rate of 84%, compared to 48% for the 12 patients who received less than 6000 rads. These results indicate that a subgroup of breast cancer patients can be identified that has a high risk of local recurrence when an insufficient radiation dose (i.e., less than 6000 rads) is delivered to the primary tumor area.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0732-183X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
1
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
|
pubmed:pagination |
184-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:6321680-Actuarial Analysis,
pubmed-meshheading:6321680-Axilla,
pubmed-meshheading:6321680-Breast Neoplasms,
pubmed-meshheading:6321680-Carcinoma, Intraductal, Noninfiltrating,
pubmed-meshheading:6321680-Dose-Response Relationship, Radiation,
pubmed-meshheading:6321680-Female,
pubmed-meshheading:6321680-Follow-Up Studies,
pubmed-meshheading:6321680-Humans,
pubmed-meshheading:6321680-Lymphatic Metastasis,
pubmed-meshheading:6321680-Neoplasm Recurrence, Local,
pubmed-meshheading:6321680-Risk
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pubmed:year |
1983
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pubmed:articleTitle |
Clinical-pathologic study of early breast cancer treated by primary radiation therapy.
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pubmed:publicationType |
Journal Article,
Comparative Study
|