Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1984-3-7
pubmed:abstractText
The concept of the brain as an endocrine target organ is not new, nor is it novel to consider the circumventricular organs as receptive regions of the brain for circulating substances. However, in this review we have emphasized the relatively novel concept that CVOs mediate exclusively the direct feedback actions of circulating peptide hormones on brain function. In addition we have presented speculations concerning the neural mechanisms by which signals arising from peptide hormone-receptor interaction might be relayed into the CNS, and indicated the possible involvement of CVO receptors in endocrine disorders. We hope that this analysis provides a conceptual framework for evaluating the functional relationship of circulating peptides to brain and inspires interest in this fascinating area of neuroendocrinology.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0065-2903
pubmed:author
pubmed:issnType
Print
pubmed:volume
10
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
269-89
pubmed:dateRevised
2009-11-19
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Circumventricular organs: receptors and mediators of direct peptide hormone action on brain.
pubmed:publicationType
Journal Article, Review